Xavier Siebert's
(Old) Homepage
*NEW* Contact info (as of 2007)
Methods and Electron Microscop
y
group (with Jorge Navaza)
Laboratory of Structural Electron Microscopy
(room 6234)
Institut for Structural Biology
UMR 5075, CNRS
41, rue Jules Horowitz
F-38027 Grenoble - Cedex 1
France
T :
(++33)-(0)4-38.78.01.58
F :
(++33)-(0)4-38.78.54.94
E :
xavier.siebert _AT_ ibs.fr
W :
http://mem.ibs.fr/XS
Research Interests (click
here
for details)
Methodological developments for structural biophysics (X-ray crystallography / Electron Microscopy) :
UROX
(with Jorge Navaza)
Structural studies (X-ray crystallography) of peptidylglygine amidating monooxygenase (with
Mario Amzel
,
Sean Prigge
,
Ninian Blackburn
,
Betty Eipper and Richard Mains
)
Statistical mechanics of macromolecular association (with
Mario Amzel
)
Water structure and hydrophobic effects (with
Gerhard Hummer
)
Curriculum Vitae
[ps]
[pdf]
PhD Thesis
[pdf]
(you will need a password for this, just ask me)
Publications
Trapani S., Siebert X., Navaza J. "The concept of resolution in the domain of rotations.", Acta Cryst. A. (2007) Mar;63(Pt 2):126-30
Siebert X., Eipper B.A., Mains R.E., Prigge S.T., Blackburn N.J. and Amzel L.M. ``The catalytic copper of Peptidylglycine alpha-Hydroxylating Monooxygenase also plays a critical structural role.'', Biophysical Journal (2005);89(5):3312-9.
Amzel L.M., Siebert X, Armstong A.A. and Pabon G.
"Thermodynamic Calculations in Biological Systems."
, Biophysical Chemistry (2005), 117:137-152.
Siebert X. and Amzel L. M.
"Loss of translational entropy in molecular associations."
, Proteins (2004),54(1):104-15.
Siebert X. and Hummer G.
"Hydrophobicity maps of the N-peptide coiled coil of HIV-1 gp41."
, Biochemistry (2002), 41(9):2956-61
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