The Slides Production Facility core at Johns Hopkins University produces poly-ethylene glycol (PEG) passivated glass and quartz slides for microscopy. PEG passivated surfaces prevent non-specific binding of proteins and nucleic acids, permitting only specific interactions provided a small fraction of functionalized PEG molecules. Typical PEG-slide production is labor and time intensive, and is a low throughput process producing about 10 slides for a day’s work. We have scaled up the production throughput, producing as many as 60 slides for the same amount of time. Bulk production is also more cost effective.
The facility charges $32 for a PEG-passivated quarts slide and glass coverslip pair, far lower than commercially available similar products, which cost $100.
At present, we are able to meet the demands of on an average, 40 slides per week, but home to scale that up soon.
The above picture is a typical assembled slide-coverslip pair, with 5 “channels” for flowing microscopy reagents through.