Xiao Group

Singleton SF., Roca AI., Lee AM., Xiao J., Probing the structure of RecA-DNA filaments. Advantages of a fluorescent guanine analog. Tetrahedron, 2007, 63(17):3553-3566

Xiao J ., Elf, J., Li, G., Yu, J., Xie X. S., Imaging gene expression in living cells at the single molecule level. Single Molecules: A Laboratory Manual, edited by Selvin P., and Ta H. 2007, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.

Yu J., Xiao J., (equal contribution), Ren X., Lao K., Xie X.S., Probing gene expression in live E. coli cells: one molecule at a time. Science, 2006, 311(5767):1600-3.
         In the News:
             Borman, S. “Chemistry Highlights 2006” (Cover Story), Chemical & Engineering News (Dec. 18, 2006).
             More here!

Xiao J., Lee, A., Singleton SF. Direct evaluation of a kinetic model for RecA-mediated DNA-strand exchange: the importance of nucleic acid dynamics and entropy during homologous genetic recombination. Chembiochem. 2006, 7(8):1265-78.

Xiao J., Lee, A., Singleton SF. Construction and evaluation of a kinetic scheme of RecA mediated DNA strand exchange. Biopolymers. 2006, 81(6):473-96.

Lee A., Xiao J., Singleton SF. Origins of sequence selectivity in homologous genetic recombination: insights from rapid kinetic probing of RecA-mediated DNA strand exchange. J Mol Biol. 2006, 360(2):343-59.

Xiao J., Singleton SF., Elucidating a key intermediate in homologous DNA strand exchange: structural characterization of the RecA?triple-stranded DNA complex using fluorescence resonance energy transfer. J. Mol. Biol, 2002 Jul 12;320(3):529-58.

Singleton SF., Xiao J., The Stretched DNA geometry of recombination and repair nucleoprotein filaments. Biopolymers, 2001-2002;61(3):145-58.

Martin SR, Lu AQ, Xiao J, Kleinjung J, Beckingham K, Bayley PM., Conformational and metal-binding properties of androcam, a testis-specific calmodulin-related protein from Drosophila. Protein Science, 1999, Nov 8(11):2444-54.