July 14, 2016
Jennifer Kavran
Research Interests: I am intrigued by how cells receive information from their environment and how they then process and respond to that information. This phenomenon, known as signaling, underlies numerous biological processes and allows cells to react to external cues […]
July 8, 2016
Scott Bailey
Research Interests Research in the Bailey laboratory focuses on the molecular basis of the processes that relate to protein nucleic acid interaction. The strategy that we use is based primarily on structural studies using X-ray crystallography. A central premise of […]
February 24, 2016
Cynthia Wolberger
Research Interests Protein function is dynamically regulated in the cell by reversible posttranslational modifications. We are interested in the mechanism by which chromatin modifications regulate transcription, nucleosome dynamics and the response to DNA damage. A particular focus is on the […]
February 24, 2016
Jungsan Sohn
Research Interests We are interested in understanding mechanisms that allow biological stress-sensors to detect danger signals and initiate highly coordinated coping-responses by assembling into higher order molecular assemblies. Innate immunity is the first line of defense against invading pathogens in […]
February 24, 2016
Albert Lau
Research Interests Our lab uses a combination of computational and experimental approaches to try to understand the atomic and molecular details governing the function of protein complexes involved in intercellular communication. The complexes that are studied include ionotropic glutamate receptors […]
February 24, 2016
Dominique Frueh
Research Interests Our laboratory uses nuclear magnetic resonance (NMR) to study modulations of protein dynamics and conformations in active enzymatic systems. Non-ribosomal peptide synthetases (NRPSs) are large enzymatic systems responsible for the biosynthesis of a wealth of secondary metabolites, many […]
February 24, 2016
James M. Berger
Research Interests My laboratory’s research is focused on understanding how multi-subunit assemblies use ATP for overcoming topological challenges within the chromosome and controlling the flow of genetic information. We are particularly interested in developing mechanistic models that explain how macromolecular […]
